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Patient - Trusted medical information and support. Making lives better dave64969, for 30 years I was hypothyroid and did fine on a high dose around 250 mg daily. Two years ago I started the well known "foggy head, tired all day" syndrome. I'm synthroid migraines seeing a good endocrinologist but nothing works. My levels are synthroid migraines normal at 190 mg daily. He cautions against a higher dose because of the danger of osteoporosis etc. Still, I wonder how I would feel on a radically higher dose. Has anyone tried it? I'm thinking 300 mg daily maybe? Please share any relevant experiences. Dave, report this 0, that could send you into hyperthyroid. Report this 0, hi Dave, my experience with Synthroid and levothyroxin was that it worsened the thyroid autoimmune response. So as I increased the dose, the meds became less effective, as my immune system reacted more to them. I ended up on a very high dose, but still had hypo symptoms so I went off the levo and tried other things. Eventually, I dumped the meds completely. However, there are some controversial protocols using high doses of T4 or NDT temporarily to desensitize the immune system by going extremely hyperthyroid for a short period of time, resulting in lowering thyroid resistance, and hence much lower doses that are still effective. In all, the reason doc's are hesitant to prescribe high doses of thyroid meds is due to the fact that side effects increase as the dose increases. So you basically increase your odds of a serious illness due to the meds. My dose was very high and I ended up with multiple fractures and breaks in my foot due in part to bone deterioration caused by high doses of medication. Report this 0, i agree with Madski. . If your hormone levels are where they should be, you don't need more hormones. . That's all that Synthroid is (a synthetic hormone). . I'm about to get a little "hippie" on you but you might want to consider your dietary intake. . You may be low in certain vitamins - possibly vitamin. I barely have any Hashimoto's symptoms yet" I'm told but I've been a pescatarian for.5 years and upon receiving my diagnosis of hypothyroidism in early October of this year, I've decided to try a gluten-free diet. . I began some herbal supplements after doing some research, and starting taking a Vitamin B Complex and. . I'm 5'3 and was around 150 lbs at the time of diagnosis. . I weighed in today at 137. .
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